Neuro-stimulation is used in research and clinical applications. Neuroscientists use nerve stimulation to answer fundamental questions about the functions of the nervous system and diseases such as Alzheimer’s and biological processes. Electrical stimulation has traditionally served as the standard method to stimulate neural tissue; but researchers have developed an optical technique called transient optical nerve stimulation.

                           Transient optical nerve stimulation is a technique that optically stimulates neural tissue using mid-infrared light. The method relies on direct but transient (non contact) irradiation of nerve surface. The laser uses an optimized radiant exposure and wavelength to generate action potentials and physiological effects.

Stimulation is the irritation action of various agents on muscles, nerves, by which the activity is evoked; especially, the nervous impulse produced by various agents on nerves, by which the part connected with the nerve is set into a state of activity.

We describe the evolution of lasers in nerve stimulation is this induction of neural damage by electrical stimulation. The Electrophysiological recordings resulted in a                                                signal that contains a stimulus-induced artifact and hence required signal processing.

                       These limitations have driven researchers to pursue other means for neural stimulation, including magnetic, ultrasound, lasers and other mechanical methods. Researchers are studying to use laser light to stimulate and control nerve cells. This optical technique is known as transient -optical nerve stimulation - a non-contact approach to neural activation.

It is a technique that optically stimulates neural tissue using mid-infrared light. The method relies on the direct but transient irradiation of the nerve surface. The laser uses an optimized radiant exposure and wavelength to generate action potentials and subsequent physiological effects; for example, muscle contraction. The response is spatially precise permitting selective targeting of individual nerve with no observed tissue damage and exhibits no stimulation artifacts.

Electrical stimulation excites the entire nerve and elicits a subsequent twitch response from all innervated muscles, where as optical stimulated response is specific.

         Finally, the transient optical nerve stimulation is declared to be safe with no neurological functional deficit.