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Anil Peddi
Bone cements are polymeric materials that are extensively used for the fixation of components of arthroplasties. The materials are usually based on methylmetacrylate (MMA) monomer and a prepolymer powder, mainly poly(methyl methacrylate) (PMMA) that - after mixing - cure in situ. The cured cements are weight-bearing and load-transferring, and therefore their mechanical behavior plays a critical role in the implant outcome. Registry studies have shown that implant loosening often is related to cement failure (Espehaug, 2002; Havelin, 1995). Today, the clinical performance of new bone cements is basically revealed only by clinical registries of implant survival, as was the case with a bone cement using a new formulation (Boneloc).
The ultimate goal of this project is to identify parameters, as revealed by preclinical testing that can predict clinical outcome of bone cements. The aims are:
- To investigate the time-dependent mechanical properties of a commonly used bone cement
- To assess the influence of testing conditions on the mechanical behavior of cements
- To characterize bone cement retrieved from revision operations
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